Yes, there is a Replication Agent for DB2 z/OS available. The RA scans the active ( and archive ) DB2 transaction log using IBM's IFI interface and transmits the information in the SRS LTL via TCP to the Replication Server.
DDL Replication is also supported. I have a test environment in place for a DB2 z/OS to HANA Replication.
Works really good,
Best regards
T